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Directions of Fluocinonide Ointment

[Drug name]
General name: Fluocinonide Ointment
English? name: Fluocinonide Ointment
Chinese pronunciation name :Cusuan Fuqingsong Ruangao
The main ingredient and chemical name: 6α,9-Difluoro-11β, 16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione,cyclic 16,17-acetal with acetone,21-acetate
Chemical structure:

Molecular formula: C26H32F2O7
Molecular weight: 494.53
[Description] a white ointment of emulsion base.
[Pharmacology and Toxicity] Adrenal cortical hormone drugs. External administrated it can contract the blood capillary of dermis, Inhibit the epidermic cell proliferation and? regeneration, and? inhibit the connective tissue ieward fibrocyte newly born, make ieward membrane of lysosome stable,prevent the tissue injury caused by lysosomal nzyme releasing. It has potent antiinflammation and antihypersensitivity effect.
[Indication]? It is adrenal cortical hormone drugs. It is available to Sensitization dermatitis,? atopic dermatitis,Contact dermatitis,seborrheic dermatitis,eczema, Pruritus of skin, Psoriasis, neurodermatitis etc..
[Administration and dosage] Applied to lesion area Twice daily. Block therapy is only applicable for chronicity thickening and skin injury of palmaris et plantaris。
[Adverse reaction] long time or large area administrated, adermotrophia and telangiectasia can be caused. It is to be happened that Acneform dermatitis, folliculitis, perioral dermatitis. predisposition increasing. Allergic reaction and contact dermatitis may rarely occur.
[Contraindication] patients with Fungal and viral dermatitis, hypersensitivity to this drug, base, and other corticosteroid.
[Precaution] 1.If apply to damaged skin for long time,it would be absorbed and have effects over the total body.?
2. It should be administrated in alliance with antibiotics to treat dermatosis complicated with bacterial infection. Withdraw if infection isn't improved.?
3. don't be in long time and large area use.
[Pregnancy and lactation] Administrated cautiously after weigh the merits and demerits.
The drug should not be use for pregnant in long time , large area or large dosage therapy.
[Pediatric Use]? If lesion area in children and babies is larger, reduce the dosage and therapy time if possible. Block therapy is not permitted。
[Drug interaction]? Not? be? defined.
[Overdoge]? the maximum weekly dose is 50g cream. Administrated many times daily and continue several days, tolerance happen. It had not better be administrated frequently daily.?? Interrupted administrated.
[Specification] 10g : 2.5mg ; 20g :5mg.
[Storage] tightly sealed. Keep in a cool place.
[Package] supplied in a plastic tube. 10g per tube in a box;20g per tube in a box.
[Validity] 3 years
[Approval number] Guo Yao Zhun Zi H12020838
[Manufacturer]
Manufacturer name :TIANJIN PACIFIC PHARMACEUTICAL CO., LTD.
Add.:? Bridge No.17 Outer circular Line, Jiefang South Road, Tianjin,China.
PC.: 300385
Tel.: (022)23971657
Fax: (022)23979013
http://www.anyugj.com